Columbia University
Engineering next-generation biomolecular immunotherapies
We integrate protein engineering, synthetic biology, and biomaterials to address challenges in cancer and infectious diseases, engineering RNA- and protein-based platforms that precisely modulate immune responses and improve therapeutic efficacy.
Our approach
Where disciplines meet
Biomolecular
Immunotherapies
Synthetic biology
RNA-based gene circuits that sense and respond to their environment.
Protein engineering
Designer proteins that precisely modulate immune responses.
Biomaterials
Engineered biopolymers for controlled, depot-forming delivery.
Biomolecular engineering
RNA- and protein-based platforms for next-generation therapeutics.
Research
Three core research areas

01
RNA circuits for the tumor microenvironment
Rewiring immunosuppressive tumors into inflammatory ones.
Visit us
Find the lab
Yousefpour Lab
Columbia University
Mary Woodard Lasker Biomedical Research Building, Room 516
3960 Broadway, New York, NY 10032
Contact
Get in touch
Parisa Yousefpour, Principal Investigator
py2339 [at] columbia [dot] edu
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